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子宮峽部缺損合併膀胱子宮內膜異位症 之腹腔鏡治療:個案報告

2026.03.28
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發表日期:2026/3/28
發表人:婦產科 吳加仁醫師、張紅淇醫師
發表場合:台灣婦產科醫學會年會

Introduction

    Isthmocele, or cesarean scar defect, is a pouch-like defect located at the anterior uterine isthmus following cesarean section. It is associated with abnormal uterine bleeding, chronic pelvic pain, dysmenorrhea, and secondary infertility. 
    Bladder endometriosis represents a rare manifestation of endometriosis and may arise from direct implantation during pelvic surgery or as part of deep infiltrating disease. The coexistence of isthmocele and bladder endometriosis is uncommon, and the underlying pathophysiology remains poorly understood.


Case Presentation

    A postpartum woman with a history of cesarean section due to placenta accreta presented with pelvic pain and more vaginal discharge. She denied gross hematuria but reported cyclical exacerbation of pelvic discomfort. The ultrasonography and hysteroscopy revealed a myometrial defect at the anterior lower uterine segment consistent with an isthmocele, with heterogenic content. (Fig 1) Additionally, a homogeneous mass was noted on the posterior bladder wall, raising suspicion for bladder endometriosis. (Fig 2) After counseling, the patient elected to undergo surgical management.

子宮峽部缺損合併膀胱子宮內膜異位症之腹腔鏡治療:個案報告

Surgical Technique

    Laparoscopic surgery was performed under general anesthesia. Dense adhesions were identified at the vesicouterine fold. (Fig 3) Careful adhesiolysis allowed separation of the bladder from the lower uterine segment. The fibrotic tissue of the isthmocele was excised to expose healthy myometrium, followed by layered repair of the uterine defect using non-locking sutures to restore uterine wall thickness. 
    Bladder endometriosis was managed using a bladder shaving technique, as there was no evidence of mucosal involvement via cystoscopic examination.  (Fig 4)
    The endometriotic nodule was completely excised without entering the bladder lumen. Bladder integrity was confirmed intraoperatively.

子宮峽部缺損合併膀胱子宮內膜異位症之腹腔鏡治療:個案報告

Postoperative Course

    The patient had an uneventful postoperative recovery. Her pelvic pain and vaginal discharge significantly improved during follow-up. No urinary complications were noted. She was advised to delay pregnancy for at least 3–6 months and underwent follow-up imaging to assess scar healing. 


Discussion

Pathophysiology

Several mechanisms may explain the association between isthmocele and bladder endometriosis:
Iatrogenic implantation of endometrial cells during cesarean section.
Menstrual blood pooling within the isthmocele acting as a reservoir for endometrial implantation.
Secondary invasion of endometriotic tissue into the bladder wall.
Bladder endometriosis can be classified as primary or secondary, with secondary forms commonly associated with prior pelvic surgery.

Diagnostic Challenges

    Bladder endometriosis may mimic bladder tumors and is often overlooked, especially in women with urinary or pelvic symptoms following cesarean delivery.
    The ultrasonography remains the first-line diagnostic modality, while MRI is useful for mapping deep infiltrating disease.

Surgical Considerations

    Surgical excision remains the definitive treatment for bladder endometriosis. The bladder shaving technique is appropriate when the mucosa is not involved, whereas partial cystectomy is reserved for full-thickness disease.  
    Multidisciplinary planning and meticulous dissection are crucial to minimize complications.


Conclusion

    This case illustrates a rare but clinically significant coexistence of cesarean scar isthmocele and bladder endometrioma. Awareness of this association is essential for timely diagnosis. Laparoscopic excision of bladder endometriosis combined with repair of the cesarean scar defect provides excellent symptom relief and favorable outcomes.

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